This initiative, to be launched in 2026 at IEAC-UNIFESP, aims to promote discussions and the production of content on the current challenges in scientific research that are common across all fields of knowledge, as well as potential solutions for generating high-quality scientific knowledge. Examples of these challenges, which will be the focus of this group, include issues such as the replicability crisis, the reduction of funding allocated to research, the lack of representativeness of researchers and samples from outside the Global North, the growing distance between science and society, and the increasing pressure placed on researchers to publish, which has led to questionable scientific practices.